Recasting biomolecules for function.

D the holiday season, transformations abound. At the end of the year, my family, friends, and colleagues parade in their ugly sweaters or their New Year’s Eve party-wear. I was thinking about how these adornments can influence our circle of interactions. As a tangible example, my colleague George Phillips attracted a crowd with his prize-winning sweater (Figure 1). Our first issue of 2012 also focuses on